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DIPHOSPHONATES
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DeCS
Descriptor
English
:
Diphosphonates
Descriptor
Spanish
:
Difosfonatos
Descriptor
Portuguese
:
Difosfonatos
Synonyms
English
:
Bisphosphonates
Tree Number:
D02.705.429.500
Definition
English
:
Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds
affect
calcium
metabolism
. They inhibit ectopic calcification and slow down
bone resorption
and bone turnover.
Technetium
complexes of
diphosphonates
have been used successfully as bone scanning agents.
Pharmacological Action:
Bone Density Conservation Agents
History Note
English
:
77
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
4220
Unique Identifier:
D004164
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS