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DEFIBRASE
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DeCS
Descriptor
English
:
Batroxobin
Descriptor
Spanish
:
Batroxobina
Descriptor
Portuguese
:
Batroxobina
Synonyms
English
:
Defibrase
Reptilase
Reptilase-DEF
Reptilase DEF
Defibrol
Hemocoagulase
Tree Number:
D08.811.277.656.300.760.955.135
D08.811.277.656.959.350.955.135
D20.888.850.960.200.105
D23.946.833.850.960.200.105
Definition
English
:
A proteolytic enzyme obtained from the venom of fer-de-lance (
Bothrops
atrox). It is used as a
plasma
clotting agent for
fibrinogen
and for the
detection
of
fibrinogen
degradation products. The presence of
heparin
does not interfere with the clotting test. Hemocoagulase is a mixture containing
batroxobin
and
factor X
activator. EC 3.4.21.-.
Pharmacological Action:
Fibrinolytic Agents
Hemostatics
History Note
English
:
2000(1975); for PLASMOCOAGULASE use BATROXOBIN (NM) 1979-1999
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
23451
Unique Identifier:
D012103
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS