Search on: CYTARABINE 
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Descriptor English:   Cytarabine 
Descriptor Spanish:   Citarabina 
Descriptor Portuguese:   Citarabina 
Synonyms English:   Aracytidine
Aracytine
Cytarabine Hydrochloride
Cytonal
Cytosar
Cytosar-U
beta-Ara C
Arabinoside, Cytosine
Cytosar U
CytosarU
Hydrochloride, Cytarabine
Ara-C
Arabinofuranosylcytosine
Arabinosylcytosine
Cytosine Arabinoside  
Tree Number:   D03.383.742.680.245.453
D13.570.065.300
D13.570.685.245.453
Definition English:   A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472) 
Pharmacological Action:   Antimetabolites, Antineoplastic
Antiviral Agents
Immunosuppressive Agents
 
History Note English:   66 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   3578 
Unique Identifier:   D003561 

Occurrence in VHL:
 

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