Search on: CAFFEINE 
Descriptors Found: 1
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Descriptor English:   Caffeine 
Descriptor Spanish:   Cafeína 
Descriptor Portuguese:   Cafeína 
Synonyms English:   1,3,7-Trimethylxanthine
Berlin-Chemie Brand of Caffeine
Bristol-Myers Squibb Brand of Caffeine
Caffedrine
Coffeinum N
Coffeinum Purrum
Dexitac
Durvitan
GlaxoSmithKline Brand of Caffeine
Merck dura Brand of Caffeine
No Doz
Passauer Brand of Caffeine
Percoffedrinol N
Percutaféine
Pierre Fabre Brand of Caffeine
Quick-Pep
Republic Drug Brand of Caffeine
Seid Brand of Caffeine
Thompson Brand 1 of Caffeine
Thompson Brand 2 of Caffeine
Vivarin  
Tree Number:   D03.132.960.175
D03.633.100.759.758.824.175
Definition English:   A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling. 
Pharmacological Action:   Central Nervous System Stimulants
Phosphodiesterase Inhibitors
Purinergic P1 Receptor Antagonists
 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   2143 
Unique Identifier:   D002110 

Occurrence in VHL:
 

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