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BUTYROPHILINS
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DeCS
Descriptor
English
:
Butyrophilins
Descriptor
Spanish
:
Butirofilinas
Descriptor
Portuguese
:
Butirofilinas
Synonyms
English
:
Butyrophilin
Tree Number:
D12.776.395.550.114
D12.776.543.550.195
Definition
English
:
A
family
of mammalian
membrane glycoproteins
characterized by extracellular
IMMUNOGLOBULIN DOMAINS
. Some members also have an intracellular B30.2-SPRY DOMAIN or SPRY DOMAIN. The
butyrophilin
protein (BTN) is expressed by MAMMARY GLAND
EPITHELIUM
during
LACTATION
; whereas other members are widely expressed in other
tissues
, including skeletal muscle,
intestine
,
ERYTHROID CELLS
(ERMAP protein); and
nerve tissue
(
MYELIN-OLIGODENDROCYTE GLYCOPROTEIN
).
History Note
English
:
2017 (1981)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56620
Unique Identifier:
D000071797
Occurrence in VHL
:
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