Search on: BUPROPION 
Descriptors Found: 1
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Descriptor English:   Bupropion 
Descriptor Spanish:   Bupropion 
Descriptor Portuguese:   Bupropiona 
Synonyms English:   (+-)-1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone
Amfebutamone
Bupropion Hydrochloride
Bupropion Hydrochloride, (+-)-Isomer
Bupropion, (+-)-Isomer
Quomen
Wellbutrin
Zyban (Anti-Smoking)
Zyntabac  
Tree Number:   D02.522.818.110
Definition English:   A unicyclic, aminoketone antidepressant. The mechanism of its therapeutic actions is not well understood, but it does appear to block dopamine uptake. The hydrochloride is available as an aid to smoking cessation treatment. 
Indexing Annotation English:   do not confuse with Zyban fungicide
Pharmacological Action:   Antidepressive Agents, Second-Generation
Cytochrome P-450 CYP2D6 Inhibitors
Dopamine Uptake Inhibitors
 
See Related English:   Smoking Cessation
 
History Note English:   92; was BUPROPION (NM) 1978-91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   30220 
Unique Identifier:   D016642 

Occurrence in VHL:
 

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