Search on: BETA-STATHMIN 
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Descriptor English:   Stathmin 
Descriptor Spanish:   Estatmina 
Descriptor Portuguese:   Estatmina 
Synonyms English:   Alpha-Stathmin
Beta-Stathmin
Lap18 Protein
Leukemia-Associated Phosphoprotein p18
Metablastin
Oncoprotein 18
Op18 Phosphoprotein
Op18a Protein
Op18b Protein
Phosphoprotein p18
Phosphoprotein p19
Prosolin
Alpha Stathmin
Beta Stathmin
Leukemia Associated Phosphoprotein p18
Phosphoprotein, Op18
p18, Leukemia-Associated Phosphoprotein
p18, Phosphoprotein
p19, Phosphoprotein  
Tree Number:   D12.776.220.600.450.480
D12.776.624.664.700.957
D12.776.744.772
Definition English:   A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSDUCTION PATHWAYS. PHOSPHORYLATION of stathmin occurs during CELL CYCLE progression, and stathmin functions as a microtubule-destabilizing protein that promotes MICROTUBULE depolymerization during INTERPHASE and late MITOSIS. Stathmin is expressed at very high levels in a variety of human CANCERS. 
History Note English:   2006(1987) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50938 
Unique Identifier:   D050777 

Occurrence in VHL: 		 

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