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Descriptor English:   Benserazide 
Descriptor Spanish:   Benserazida 
Descriptor Portuguese:   Benserazida 
Synonyms English:   DL-Serine 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide
Ro 4-4602
Seryltrihydroxy Benzylhydrazine
Benzylhydrazine, Seryltrihydroxy
Ro 4 4602
Ro 44602
Serazide
Seryltrihydroxybenzylhydrazine  
Tree Number:   D02.442.175
Definition English:   An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone. 
Pharmacological Action:   Antiparkinson Agents
Dopamine Agents
Enzyme Inhibitors
 
History Note English:   91(79); was see under HYDRAZINES 1979-90; was SERYLTRIHYDROXY BENZYLHYDRAZINE see under HYDRAZINES 1973-78 (Prov 1973-74) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   23953 
Unique Identifier:   D001545 

Occurrence in VHL:
 

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