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B663
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DeCS
Descriptor
English
:
Clofazimine
Descriptor
Spanish
:
Clofazimina
Descriptor
Portuguese
:
Clofazimina
Synonyms
English
:
B-663
G-30,320
Lamprene
N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-((1-methylethyl)imino)-2-phenazinamine
B 663
B663
G 30,320
G30,320
Tree Number:
D03.633.300.704.353
Definition
English
:
A fat-soluble riminophenazine dye used for the treatment of
leprosy
. It has been used investigationally in combination with other antimycobacterial drugs to treat
Mycobacterium avium
infections
in AIDS
patients
.
Clofazimine
also has a marked anti-inflammatory effect and is given to
control
the
leprosy
reaction,
erythema nodosum
leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
Pharmacological Action:
Anti-Inflammatory Agents
Leprostatic Agents
History Note
English
:
74
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
3015
Unique Identifier:
D002991
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS