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AZAURIDINE
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DeCS
Descriptor
English
:
Azauridine
Descriptor
Spanish
:
Azauridina
Descriptor
Portuguese
:
Azauridina
Synonyms
English
:
2-beta-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione
6-Azauridine
6 Azauridine
Tree Number:
D02.145.451
D03.383.742.680.852.176
D13.570.685.852.176
D13.570.800.892.176
Definition
English
:
A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular
nucleic acids
. As the triacetate, it is also effective as an antipsoriatic.
Pharmacological Action:
Antimetabolites, Antineoplastic
Dermatologic Agents
History Note
English
:
73(72)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
1396
Unique Identifier:
D001380
Occurrence in VHL
:
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DeCS
CID-10
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