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ACONITINE
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DeCS
Descriptor
English
:
Aconitine
Descriptor
Spanish
:
Aconitina
Descriptor
Portuguese
:
Aconitina
Synonyms
English
:
Acetylbenzoyl-aconine
Acetylbenzoyl aconine
Acetylbenzoylaconine
Tree Number:
D02.455.849.291.037
D03.132.030
Definition
English
:
A C19 norditerpenoid alkaloid (
DITERPENES
) from the root of
ACONITUM
plants
. It activates
VOLTAGE-GATED SODIUM CHANNELS
. It has been used to induce ARRHYTHMIAS in experimental
animals
and it has antiinflammatory and antineuralgic properties.
Indexing Annotation
English
:
ACONITE (see
ACONITUM
) is also available
Pharmacological Action:
Adjuvants, Immunologic
Voltage-Gated Sodium Channel Agonists
History Note
English
:
91(75); was see under ACONITE 1975-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
164
Unique Identifier:
D000157
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS