Search on: 5-OXOPROLINASE 
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Descriptor English:   Pyroglutamate Hydrolase 
Descriptor Spanish:   Piroglutamato Hidrolasa 
Descriptor Portuguese:   Piroglutamato Hidrolase 
Synonyms English:   5-Oxoprolinase
5 Oxoprolinase
Hydrolase, Pyroglutamate
Oxoprolinase  
Tree Number:   D08.811.277.087.760
Definition English:   Hydrolyzes pyroglutamic acid in the presence of ATP to glutamate plus ADP and inorganic phosphate. Deficiency leads to pyroglutamic acidurea. 
History Note English:   91(75); was see under AMIDOHYDROLASES 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   12190 
Unique Identifier:   D011752 

Occurrence in VHL:
 

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