Expresión de búsqueda: ALPHA-MANNOSIDASE 
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Descriptor Inglés:   alpha-Mannosidase 
Descriptor Español:   alfa-Manosidasa 
Descriptor Portugués:   alfa-Manosidase 
Sinónimos Inglés:   LAMAN
Neutral alpha-Mannosidase
alpha Mannosidase B
alpha-D-Mannosidase
alpha-D-Mannoside Mannohydrolase
Lysosomal alpha Mannosidase
Mannohydrolase, alpha-D-Mannoside
Mannosidase B, alpha
Neutral alpha Mannosidase
alpha D Mannosidase
alpha D Mannoside Mannohydrolase
alpha Mannosidase
alpha-Mannosidase, Lysosomal
alpha-Mannosidase, Neutral
Lysosomal alpha-Mannosidase  
Categoría:   D08.811.277.450.625.500
Definición Inglés:   An enzyme that catalyzes the HYDROLYSIS of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. The enzyme plays a role in the processing of newly formed N-glycans and in degradation of mature GLYCOPROTEINS. There are multiple isoforms of alpha-mannosidase, each having its own specific cellular location and pH optimum. Defects in the lysosomal form of the enzyme results in a buildup of mannoside intermediate metabolites and the disease ALPHA-MANNOSIDOSIS. 
Nota de Indización Inglés:   /DEFIC: consider also ALPHA-MANNOSIDOSIS
Relacionados Inglés:   alpha-Mannosidosis
 
Nota Histórica Inglés:   2004; use ALPHA-MANNOSIDASE (NM) 1980-2003 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   38163 
Identificador Único:   D043323 

Ocurrencia en la BVS:
 

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