Expresión de búsqueda:
FOLLISTATIN
Descriptores Encontrados:
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DeCS
Descriptor
Inglés
:
Follistatin
Descriptor
Español
:
Folistatina
Descriptor
Portugués
:
Folistatina
Sinónimos
Inglés
:
Activin Binding Protein
Activin-Binding Protein
Categoría:
D12.776.157.247
Definición
Inglés
:
A broadly distributed protein that binds directly to
ACTIVINS
. It functions as an activin antagonist, inhibits
FOLLICLE STIMULATING HORMONE
secretion, regulates
CELL DIFFERENTIATION
, and plays an important role in embryogenesis.
Follistatin
is a single glycosylated polypeptide chain of approximately 37-kDa and is not a member of the inhibin
family
(
INHIBINS
).
Follistatin
also binds and neutralizes many members of the
TRANSFORMING GROWTH FACTOR BETA
family.
Nota Histórica
Inglés
:
2003; use FOLLISTATIN (NM) 1988-2002
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
37390
Identificador Único:
D038681
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS