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LEUKOTRIENE C-1
Descriptors Found:
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DeCS
Descriptor
English
:
Leukotriene C4
Descriptor
Spanish
:
Leucotrieno C4
Descriptor
Portuguese
:
Leucotrieno C4
Synonyms
English
:
Leukotriene C
Leukotriene C-1
Leukotriene C-4
Leukotriene C1
Leukotrienes C
Leukotriene C 1
Leukotriene C 4
LTC4
Tree Number:
D10.251.355.255.100.450.855.455
D10.251.355.310.166.887.855.455
D23.469.050.175.450.725.400
Definition
English
:
The conjugation product of
LEUKOTRIENE A4
and
glutathione
. It is the major
arachidonic acid
metabolite in
macrophages
and human
mast cells
as well as in antigen-sensitized lung
tissue
. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From
Dictionary
of
Prostaglandins
and Related Compounds, 1990)
Indexing Annotation
English
:
/biosyn /physiol permitted; DF: note short X ref
History Note
English
:
94; was see SRS-A 1983-93; LEUKOTRIENE C1 & LEUKOTRIENES C were see SRS-A 1983-93
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
31350
Unique Identifier:
D017997
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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