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LEUCOCIDIN
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DeCS
Descriptor
English
:
Leukocidins
Descriptor
Spanish
:
Leucocidinas
Descriptor
Portuguese
:
Leucocidinas
Synonyms
English
:
Leucocidin
Leukocidin
Leukocidin Proteins
Proteins, Leukocidin
Tree Number:
D12.776.543.695.750
Definition
English
:
Pore forming
proteins
originally discovered for toxic activity to
LEUKOCYTES
. They are
EXOTOXINS
produced by some pathogenic
STAPHYLOCOCCUS
and
STREPTOCOCCUS
that destroy
leukocytes
by lysis of the
cytoplasmic granules
and are partially responsible for the
pathogenicity
of the organisms.
Indexing Annotation
English
:
/antag permitted but consider also
ANTITOXINS
Pharmacological Action:
Cytotoxins
History Note
English
:
78; was LEUKOCIDIN 1965-77
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
8134
Unique Identifier:
D007956
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS