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CATHEPSIN B
Descriptors Found:
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DeCS
Descriptor
English
:
Cathepsin B
Descriptor
Spanish
:
Catepsina B
Descriptor
Portuguese
:
Catepsina B
Synonyms
English
:
Cathepsin B-Like Proteinase
Cathepsin B1
Cathepsin B Like Proteinase
Proteinase, Cathepsin B-Like
Tree Number:
D08.811.277.656.224.125
D08.811.277.656.262.500.133
D08.811.277.656.300.200.133
Definition
English
:
A lysosomal
cysteine
proteinase with a specificity
similar
to that of
PAPAIN
. The enzyme is present in a variety of
tissues
and is important in many physiological and pathological processes. In
pathology
,
cathepsin B
has been found to be involved in DEMYELINATION;
EMPHYSEMA
;
RHEUMATOID ARTHRITIS
, and
NEOPLASM INVASIVENESS.
History Note
English
:
87
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
23222
Unique Identifier:
D002401
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS