1 / 1
|
DeCS
|
|
|
Descriptor English:
|
|
Alarmins
|
Descriptor Spanish:
|
|
Alarminas
|
Descriptor Portuguese:
|
|
Alarminas
|
Synonyms English:
|
|
Alarmin
Alarmin Proteins
Damage-Associated Molecular Pattern Molecules
Danger-Associated Molecular Pattern Molecules
Damage Associated Molecular Pattern Molecules
Danger Associated Molecular Pattern Molecules
|
Tree Number:
|
|
D23.035
|
Definition English:
|
|
A structurally diverse group of endogenous molecules that are multifunctional, having physiological functions inside the cell, but when released from dying cells or from cells under stress or certain immune cells, they function to activate INNATE IMMUNITY. Uncontrolled and excessive release of alarmins may contribute to INFLAMMATION; CARCINOGENESIS, and NEOPLASM METASTASIS. Alarmins are also critical for heart and nerve tissue homeostasis. |
History Note English:
|
|
2016
|
Allowable Qualifiers English:
|
|
|
Record Number:
|
|
55964
|
Unique Identifier:
|
|
D000067531
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS CID-10 SciELO LILACS LIS
|